The Syndrome of Combined Pulmonary Fibrosis and Emphysema

Efficacy of aerobic physical retraining in a case of combined pulmonary fibrosis and emphysema syndrome: a case report

INTRODUCTION Combined pulmonary fibrosis and emphysema has recently been recognized as a syndrome but remains under-diagnosed. Neither clinical management nor therapeutic approaches have been clearly defined. Pulmonary rehabilitation has not been considered within the therapeutic options for combined pulmonary fibrosis and emphysema. In this case we explored the potential benefits of a specific...

Clinical characteristics in Combined Pulmonary Fibrosis and Emphysema Syndrome vs Idiopathic Pulmonary Fibrosis patients

Abstract: Aim: To identify differences between combined pulmonary fibrosis and emphysema syndrome (CPFE) and idiopathic pulmonary fibrosis (IPF) by a retrospective comparison of clinical data including clinical characteristics and baseline changes in pulmonary function. Methods: We studied demographic, clinical and physiologic features for two groups of patients, (total N=26) those with CPFE (7...

Combined Pulmonary Fibrosis and Emphysema (CPFE)

Emphysema is characterized by the permanent abnormal enlargement of airspaces distal to the terminal bronchioles, accompanied by destruction of their walls. The characteristics of emphysema do not, by definition, include thickening of the alveolar septa and fibrosis. However, coincidental idiopathic pulmonary fibrosis (IPF) and emphysema was firstly reported in 1990 by Wiggins et al (Wiggins J,...

Pulmonary hypertension in patients with combined pulmonary fibrosis and emphysema syndrome.

This study aims to describe the haemodynamic and survival characteristics of patients with pulmonary hypertension in the recently individualised syndrome of combined pulmonary fibrosis and emphysema. A retrospective multicentre study was conducted in 40 patients (38 males; age 68+/-9 yrs; 39 smokers) with combined pulmonary fibrosis and emphysema, and pulmonary hypertension at right heart cathe...

Combined pulmonary fibrosis and emphysema syndrome in a patient age 28 years with severe systemic sclerosis.

Acute exacerbation of combined pulmonary fibrosis and emphysema associated with Hermansky–Pudlak syndrome

A 30-year-old male smoker with congenital amblyopia and oculocutaneous albinism was admitted to our hospital complaining of progressive dyspnea on exertion. Chest computed tomography images revealed diffuse reticular opacities and honeycombing in the bilateral lower lobes with sparing of the subpleural region along with emphysema predominantly in the upper lobes. Lung biopsy specimens showed a ...